<P>Barry Quart could have retired in 2012 when he sold the com- pany he co-founded, Ardea Biosciences, to pharmaceutical giant AstraZeneca. He had no interest in doing so. I get bored easily, says Quart, whose latest challenge is as turnaround CEO of Heron Therapeutics, which is developing drugs to treat chemotherapy-induced nausea and postsurgical pain. SPURRING DRUG DISCOVERIES: Quarts three-decade career includes spearheading impor- tant drug discoveries against both HIV and cancer. His CV includes stints at major pharmaceutical companies like Bristol-Meyers Squibb, where he worked for more than 10 years in clinical research and regulatory affairs, as well as at small biotech- nology companies like Agouron Pharmaceuticals. At Agouron, in 1993, he helped develop Viracept, a drug that prevents HIV from replicating. It went from the lab to FDA approval in a speedy 38 months. At the time, there was a lot of pressure on FDA to move quickly, Quart notes. Protease inhibitors were key to the three- drug cocktail that changed HIV from a fatal disease to a chronic disease that no one should die from. Agouron was later acquired by Warner-Lambert for $2.1 billion. UCSF MINDSET: Quart credits his UCSF professors with teach- ing him the critical-thinking skills that lead to groundbreak- ing discoveries. They focused on questioning what youre seeing and being extremely thoughtful in coming up with analysis and decisions, he says. At Ardea Biosciences, these skills helped him see what others may have missed: that uric acid levels dropped in participants in a clinical trial of a new HIV drug, after they took the drug. Quart knew that meant part of the drug could be used to treat gout, a disease on the rise in the United States as sugar consumption has jumped. You drink a couple of Cokes and increase your uric acid levels, he says. This drug lowers uric acid, which in turn reduces gout. This serendipitous discovery led to the companys 2012 acquisi- tion by AstraZeneca. MAKING MOVIES: When hes not developing drugs, Quart pro- duces movies, as a little hobby. His most recent project, a teen comedy called Behaving Badly and starring Selena Gomez, is due out this summer. The dynamics of developing movies and drugs are remarkably similar, he says. You never know which project is going to make it. Spring 2014 | UCSF MAGAZINE45 FROM THE ARCHIVES Pharmacists in the Mof?tt Hospital pharmacy, 1959. Several years later, the School of Pharmacy would launch the ?rst clinical pharmacy program in the country. BARRY QUART, PharmD 82 Hometown: Los Angeles Now: Las Vegas Position: CEO of Heron Therapeutics Hobby: Producing ?lms RANKED THE TOP PharmD PROGRAM IN THE NATION BY U.S. NEWS & WORLD REPORT #1 IN NIH FUNDING AMONG PHARMACY SCHOOLS SINCE 1979 PIONEER IN CLINICAL PHARMACY</p> <UL><LI><a href="http://www.mzines.net/publication/618/aelvmorax/1/1/">Front-Cover</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/2/2/">Inside-Front-Cover</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/3/3/">Page-1</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/4/4/">Page-2</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/5/5/">Page-3</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/6/6/">Page-4</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/7/7/">Page-5</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/8/8/">Page-6</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/9/9/">Page-7</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/10/10/">Page-8</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/11/11/">Page-9</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/12/12/">Page-10</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/13/13/">Page-11</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/14/14/">Page-12</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/15/15/">Page-13</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/16/16/">Page-14</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/17/17/">Page-15</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/18/18/">Page-16</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/19/19/">Page-17</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/20/20/">Page-18</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/21/21/">Page-19</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/22/22/">Page-20</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/23/23/">Page-21</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/24/24/">Page-22</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/25/25/">Page-23</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/26/26/">Page-24</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/27/27/">Page-25</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/28/28/">Page-26</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/29/29/">Page-27</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/30/30/">Page-28</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/31/31/">Page-29</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/32/32/">Page-30</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/33/33/">Page-31</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/34/34/">Page-32</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/35/35/">Page-33</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/36/36/">Page-34</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/37/37/">Page-35</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/38/38/">Page-36</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/39/39/">Page-37</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/40/40/">Page-38</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/41/41/">Page-39</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/42/42/">Page-40</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/43/43/">Page-41</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/44/44/">Page-42</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/45/45/">Page-43</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/46/46/">Page-44</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/47/47/">Page-45</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/48/48/">Page-46</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/49/49/">Page-47</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/50/50/">Page-48</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/51/51/">Page-49</a></LI> <LI><a href="http://www.mzines.net/publication/618/aelvmorax/52/52/">Back-Cover</a></LI> <LI><a href="http://www.mzines.net/publications/618/x/sitemap.xml" target="_blank">site map</a></LI> </UL>

 

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