<P>Page 18 »Across the Divide »Hotez / England & Desmond / Madani / Asghar Speci?cally in regard to the seven OIC hot-spot nations listed above, cutaneous leishmaniasis is now hyperendemic in Afghanistan, Syria, and Iraq (where, because of its extreme dis?gurement when it appears on the face or other exposed parts, is sometimes known as Aleppo evil); dengue fever transmitted by Aedes mosquitoes a?ects millions in Egypt and Pakistan; and polio remains endemic in Afghanistan and Pakistan (15, 16). In addition, intestinal helminth infections are widespread where regular and periodic deworming is not conducted, and important animal infections with zoonotic potential have or could emerge, including rabies and brucellosis (15, 16). Shown in Box 1 is a new summary analysis of three major NTDs – cutaneous leishmaniasis, dengue fever, and intestinal helminth infections – in the seven hot-spot nations based on recent publications since 2012 (17–22). Overall, more than 450 million people live in these seven countries (17), of whom more than one-third live in extreme poverty (18). NTDs are widespread in this setting of con?ict and poverty. Up to 500,000 people in these seven countries su?er from cutaneous leishmaniasis, led by Afghanistan, Iran, and Syria (19). Indeed, the seven a?ected countries account for approximately 40 of the total global cases of this disease (19). Moreover, more than 20 million cases of dengue fever occur, with most of the cases in Pakistan and Egypt (20). </p> <UL><LI><a href="http://www.mzines.net/publication/643/colfslwvw/1/1/">Front-Cover</a></LI> <LI><a href="http://www.mzines.net/publication/643/colfslwvw/2/2/">Inside-Front-Cover</a></LI> <LI><a href="http://www.mzines.net/publication/643/colfslwvw/3/3/">Page-1</a></LI> <LI><a href="http://www.mzines.net/publication/643/colfslwvw/4/4/">Page-2</a></LI> <LI><a href="http://www.mzines.net/publication/643/colfslwvw/5/5/">Page-3</a></LI> <LI><a href="http://www.mzines.net/publication/643/colfslwvw/6/6/">Page-4</a></LI> <LI><a href="http://www.mzines.net/publication/643/colfslwvw/7/7/">Page-5</a></LI> <LI><a href="http://www.mzines.net/publication/643/colfslwvw/8/8/">Page-6</a></LI> <LI><a href="http://www.mzines.net/publication/643/colfslwvw/9/9/">Page-7</a></LI> <LI><a href="http://www.mzines.net/publication/643/colfslwvw/10/10/">Page-8</a></LI> <LI><a 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