<P>undamaged when dropped from a 3-story building or stepped on by a person, and can be incinerated after use. Its minimalistic, scalable GHVLJQLVLQKHUHQWO\\DSSOLFDWLRQVSHFL?FWKXVHQDEOLQJGLVHDVHVSHFL?F GLDJQRVWLFLQVWUXPHQWV7KHPLFURVFRSHXVHVHPEHGGHGPLFUR?XLGLF polymer optics, apertures, and an origami folding scheme with integrated optical, illumination, and focusing stage, all synthesized from a single sheet of A4 paper. With inherent roll-to-roll processing, manufacturing can be scaled up to billions of microscopes per year. ?QWHUIDFLDO?XLGG\\QDPLFVLVHSORLWHGWRV\\QWKHVLHJUDGLHQWLQGH optics enabling printing of microscale optical components on 2-D sheets of paper. A series of folds converts this single sheet into a fully functional optical instrument with origami-based passive alignment precision of less than 10 µm. All of this has allowed us to conceptualize a completely new paradigm for use-and-throw microscopy in global health and science education. Accessible science can only be brought to the masses if it is scalable. We are currently engaging tinkerers, thinkers, teachers, organizations, and anybody who cares about science education in a large-scale HSHULPHQWRIRXURZQ?ZHFDOOLWWKH?7HQ7KRXVDQG0LFURVFRSH Experiment. Although I realize this a drop in the ocean (thinking DERXWELOOLRQNLGVRQWKHSODQHW \\RXKDYHWRVWDUWVRPHZKHUH? remain committed to bringing microscopy to the masses one step at a time. The goal of this medium-scale experiment is subtle. We would like to engage a large crowd of amateur and professional VFLHQWLVWVWRWRJHWKHUZULWHWKH?ZRUOG?V?UVWFURZGVRXUFHGELRORJ\\ PLFURVFRS\\ODEPDQXDO?7KLVZLOOEHDUHSRVLWRU\\RIFXULRXVTXHVWLRQV microscopy observations, and aha moments written by people from all walks of life (from celebrated scientists to tinkerers to lovers RIWKHRXWGRRUVWRNLGVDVNLQJTXHVWLRQV LQDQRSHQVRXUFHIDVKLRQ from around the world. Currently, we have curious tinkerers from 130 countries around the world signed up and we are in lock step to ship 50,000 microscopes to 10,000 participants by the end of the summer. Although this is the largest undertaking I have ever engaged LQLQP\\SHUVRQDOOLIH ZKLFKEULQJVDERXWPRPHQWVRISDQLF WKH submissions and entries I receive from students and young scientists DURXQGWKHZRUOG?OOVP\\KHDUWZLWKDORWRIKRSH&RQWHWGULYHQ VFLHQFHLVDOPRVWDQHFHVVLW\\?ORFDOSHRSOHVROYLQJORFDOSUREOHPV?Q academic isolation, it is almost impossible to actually perceive what problems need to be solved in a village in Nigeria or in the heartland of Mumbai. Only by providing the means to solutions will we ever be able to bring prosperity on the planet where human beings will not Page 32 » On the Ground » Prakash </p> <UL><LI><a href="http://www.mzines.net/publication/707/arcswnjom/1/1/">Front-Cover</a></LI> <LI><a href="http://www.mzines.net/publication/707/arcswnjom/2/2/">Inside-Front-Cover</a></LI> <LI><a href="http://www.mzines.net/publication/707/arcswnjom/3/3/">Page-1</a></LI> <LI><a href="http://www.mzines.net/publication/707/arcswnjom/4/4/">Page-2</a></LI> <LI><a href="http://www.mzines.net/publication/707/arcswnjom/5/5/">Page-3</a></LI> <LI><a href="http://www.mzines.net/publication/707/arcswnjom/6/6/">Page-4</a></LI> <LI><a href="http://www.mzines.net/publication/707/arcswnjom/7/7/">Page-5</a></LI> <LI><a href="http://www.mzines.net/publication/707/arcswnjom/8/8/">Page-6</a></LI> <LI><a href="http://www.mzines.net/publication/707/arcswnjom/9/9/">Page-7</a></LI> <LI><a 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